dr. Farkas Zsolt research fellow

dr. Farkas Zsolt research fellow
Date and place of birth: 10 Dec, 1985, Budapest, Hungary
Nationality: Hungarian
Education:


 
MSc in Biology Faculty of Science, Eötvös Loránd University, Budapest (2011)
PhD title in Biology: Faculty of Science, Eötvös Loránd University, Budapest (2020)
Languages: German and English: intermediate level
MTMT id.: 10048710
ORCID id.: 0000-0001-8531-8912
Google Scholar id.: U48KQVcAAAAJ&hl
Researcher id.: AAF-9966-2020
Scopus id.: 56126526400

Workplaces

2014 - 2019  Volunteer researcher, MTA TTK

2016-2021    Assistant research fellow, Department of Biological Anthropology, Faculty of Science, Eötvös Loránd University

2022-           Research fellow, Department of Biological Anthropology, Faculty of Science, Eötvös Loránd University


Teaching activities

BSc
Human biology practise

MSc
-Physiological methodology

-Methodology of paleoanthropological studies
- Research methods of biological anthropology

PhD

-Research methods of biological anthropology


Research interest

-The effect of metastasis inhibitors of the NME gene family on cell migration, cell death, and immunomodulation.

-The role of clinically relevant SDHB mutations in the development of malignant PPGL (phaeochromocytoma and paraganglioma).


Conferences

IX. Magyar Genetikai Kongresszus és XVI. Sejt- és Fejlődésbiológiai Napok, Siófok, 2011.03.25-27. A nukleozid-difoszfát kinázt kódoló nm23-H6 (Nme6) C. elegans ortológjának genetikai analízise. Farkas Zsolt, Vellai Tibor, Vellainé Takács Krisztina

IX. Magyar Genetikai Kongresszus és XVI. Sejt- és Fejlődésbiológiai Napok, Siófok, 2011.03.25-27. Az Nm23-H1/H2 ortológ Ndk-1 aktiválja a Ras/MAPK jelátviteli útvonalat a C. elegans vulva- és gonádfejlődése során. Fancsalszky Luca, Neda Masoudi, Ehsan Pourkarimi, Monostori Eszter, Farkas Zsolt, Vellai Tibor, Anil Mehta, Anton Gartner, Alexa Anita, Reményi Attila, Takács-Vellai Krisztina. 

9th International Congress of the NDP Kinase/Nm23/awd Gene Family: A new frontier in cell and cancer biology, Boston, USA, 2013.07.31-08.04. Modelling metastatic inhibition: ndk-1/nm23-H1/H2 regulates distal tip cell (DTC) migration in C. elegans. Luca Fancsalszky, Ehsan Pourkarimi, Neda Masoudi, Maja Herak Bosnar, Martina Dezeljin, Zsolt Farkas, Tibor Vellai, Anil Mehta, Krisztina Takács-Vellai

Magyar Humángenetikai Társaság X. Jubileumi Kongresszusa, Budapest, 2014. szeptember 4-6. Az NM23 homológ NDK-1 sejtmigrációban és apoptózisban betöltött szerepe. Fancsalszky Luca, Farkas Zsolt, Maja Herak Bosnar, Vellai Tibor, Anil Mehta, Takács-Vellai Krisztina

19th World Congress on Advances in Oncology and 17th International Symposium on Molecular Medicine October 9-11, 2014 Metropolitan Hotel, Athens, Greece. Characterizing the role of the NM23 homolog NDK-1 in cell migration and apoptotic engulfment. L. Fancsalszky, Z. Farkas, M.H. Bosnar, T. Vellai, A. Mehta, K. Takács-Vellai

Hungarian Molecular Life Sciences 2015, Eger, 2015.03.27-29. Characterizing the role of the NM23 homolog NDK-1 in cell migration and apoptotic engulfment. Zsolt Farkas, Luca Fancsalszky, Sára Sándor, Tamás Orbán, Maja Herak Bosnar, Tibor Vellai, Anil Mehta, Krisztina Takács-Vellai

The Inter Congress of the International Union of Anthropological and Ethnological Sciences, Dubrovnik, 2016.05.04-09. An investigation of extracellular NM23. Zsolt Farkas, Anna Sebestyén, Edit I. Buzás, Maja Herak Bosnar, Zoltan Prohaszka and Krisztina Takács-Vellai

Tavaszi Szél 2016 Nemzetközi Multidiszciplináris Konferencia, Budapest, 2016. április 15-17. AZ NM23 HOMOLÓG NDK-1 SEJTMIGRÁCIÓRA GYAKOROLT DÓZISFÜGGŐ HATÁSÁNAK VIZSGÁLATACAENORHABDITIS ELEGANSBAN. GRÁFAlexandra, VELLAINÉ TAKÁCS Krisztina, FARKAS Zsolt

International Congress of the NDP Kinase/Nm23/Awd Family (NDPK2016). Dubrovnik, Croatia, October 9-13, 2016. The dosage dependent effect of NDK-1/NM23-H1/H2 exerted on cell migration in C. elegans. Zsolt Farkas, Luca Fancsalszky, Alexandra Gráf, Barbara Mátyási, Maja Herak Bosnar, Tibor Vellai, Anil Mehta, Krisztina Takacs-Vellai

International Congress of the NDP Kinase/Nm23/Awd Family (NDPK2016). Dubrovnik, Croatia, October 9-13, 2016. The C. elegans group I NDPK homologue NDK-1 functions together with DYN-1/Dynamin. Zsolt Farkas, Tamás Végh, Xianghua Liu, Sung Yun Jung, Muhammed Afaq Shakir, Mathieu Boissan, Jun, Qin, Zheng Zhou, Krisztina Takacs-Vellai

Hungarian Molecular Life Sciences 2017, Eger, 2017.03.31-2017.04.02. The C. elegans group I NDPK homologue NDK-1 functions together with DYN-1/Dynamin in apoptotic engulfment and clearance. Zsolt Farkas, Xianghua Liu, Sung Yun Jung, Muhammed Afaq Shakir, Tamás Végh, Sára Sándor, Tamás Orbán, Mathieu Boissan, Jun Qin, Zheng Zhou, Krisztina Takacs-Vellai

Új Nemzeti Kiválóság Program konferencia, ELTE, 2018.05.24. NDK-1/NDPK interakciós partnereinek azonosítása, az NDK-1 DYN-1 kölcsönhatás szerepe a membránátrendezési folyamatokban. Farkas Zsolt, Vellainé Takács Krisztina

Genetikai Műhelyek Magyarországon XVII. Minikonferencia, Szeged, 2018.09.21. A C. elegans NDK-1/NDPK  DYN-1 kölcsönhatás szerepe a membránátrendezési folyamatokban. Farkas Zsolt, Vellainé Takács Krisztina


Role and activity in scientific communities

2011 -  Association of Hungarian Geneticists, member

Scholarships

Richter Gedeon Centenar Foundation, professional training, 1 year (2012)

     State doctoral Scholarship (2013-2016)

     Eötvös Loránd University, Scientific Scholarship (multiple times)

NDPK2016 conference sponsorship award (ICGEB)

Fundings

-OTKA (Hungarian Research Fund) 2015-2020 – co-applicant

-ÚNKP (New National excellence program) 2017, (10 months)

-Find a cure / Pheo Para Cancer Charity found (2016-) – co-applicant

-Institutional Excellence Program (2018-) – co-applicant

-OTKA (K134285) 2020-2025– co-applicant

-EKÖP-2024 UNIVERSITY EXCELLENCE SCHOLARSHIP PROGRAM, 12 months postdoc scholarship


Selected publications (10)

Fancsalszky L, Monostori E, Farkas Z, Pourkarimi E, Masoudi N, Hargitai B, Bosnar MH, Dezeljin M, Zsakai A, Vellai T, Mehta A, Takacs-Vellai K. 
NDK-1, the Homolog of NM23-H1/H2 Regulates Cell Migration and Apoptotic Engulfment in C. elegans. 
PLOS ONE 9:(3) p. e92687. 12 p. (2014) 
IF: 3,53

Takács-Vellai KVellai TFarkas ZMehta A
Nucleoside diphosphate kinases (NDPKs) in animal development. 
CELLULAR AND MOLECULAR LIFE SCIENCES 72:(8) pp. 1447-1462. (2015). 
IF: 5,856

Farkas Z, Fancsalszky L, Saskői É, Gráf A, Tárnok K, Mehta A, Takács-Vellai K. 
The dosage-dependent effect exerted by the NM23-H1/H2 homolog NDK-1 on distal tip cell migration in C. elegans. 
LABORATORY INVESTIGATION 98(2):182-189. (2018) 
IF: 4,857

Farkas Z, Petric M, Liu X, Herit F, Rajnavölgyi É, Szondy Z, Budai Z, Orbán TI, Sándor S, Mehta A, Bajtay Z, Kovács T, Jung SY, Afaq Shakir M, Qin J, Zhou Z, Niedergang F, Boissan M, Takács-Vellai K. 
The nucleoside diphosphate kinase NDK-1/NME1 promotes phagocytosis in concert with DYN-1/dynamin.
FASEB JOURNAL fj.201900220R [Epub ahead of print] (2019) 
IF 5,498

Mátyási B, Farkas Z, Kopper L, Sebestyén A, Boissan M, Mehta A, Takács-Vellai K.
The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis.
Pathol Oncol Res. 2020 Jan 28. doi: 10.1007/s12253-020-00797-0. [Epub ahead of print]  
IF: 2,433

Lukácsi S, Farkas Z, Saskői É, Bajtay Z, Takács-Vellai K
Conserved and Distinct Elements of Phagocytosis in Human and C. elegans
Int J Mol Sci . 2021 Aug 19;22(16):8934. doi: 10.3390/ijms22168934.
IF:5,923

Takács-Vellai K, Farkas Z, Ősz F, Stewart G W
Model systems in SDHx-related pheochromocytoma/paraganglioma
Cancer Metastasis Rev . 2021 Dec;40(4):1177-1201. doi: 10.1007/s10555-021-10009-z.
IF: 9,264

Mátyási B, Petővári G, Dankó T, Butz H, Likó I, Lőw P, Petit I, Bittar R, Bonnefont-Rousselot D, Farkas Z, Szeniczey T, Molnár K, Pálóczi K, Buzás I E, Boissan M, Sebestyén A, Takács-Vellai K
Extracellular Vesicle-Mediated Metastasis Suppressors NME1 and NME2 Modify Lipid Metabolism in Fibroblasts
Cancers (Basel) . 2022 Aug 13;14(16):3913. doi: 10.3390/cancers14163913.
IF:6,86

 

Ősz F ; Nazir A ; Takács-Vellai K ; Farkas Z
Mutations of the Electron Transport Chain Affect Lifespan and ROS Levels in C. elegans
ANTIOXIDANTS 14 : 1 Paper: 76 (2025)
IF: 6.0